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Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.
Tularemia cases in the U.S. rose by 56% from 2011 to 2022, with central states and American Indian communities most affected, highlighting diagnostic advancements and health disparities.
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Nature Mental Health, Published online: 03 January 2025; doi:10.1038/s44220-024-00356-5 This umbrella review synthesizes a large body of evidence on adverse outcomes in over 31 million people with traumatic brain injury and identifies links with dementia, perpetration of violence, and amyotrophic lateral sclerosis.
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Researchers developed AbMAP, a cutting-edge framework leveraging transfer learning to model antibody hypervariable regions, significantly improving design and immune repertoire analysis.
An ancient brain circuit, which enables the eyes to reflexively rotate up as the body tilts down, tunes itself early in life as an animal develops, a new study finds.
Researchers design a new way to more reliably evaluate AI models' ability to make clinical decisions in realistic scenarios that closely mimic real-life interactions. The analysis finds that large-language models excel at making diagnoses from exam-style questions but struggle to do so from conversational notes. The researchers propose set of guidelines to optimize AI tools' performance and align them with real-world practice before integrating them into the clinic.
A new study investigating ancient methane trapped in Antarctic ice suggests that global increases in wildfire activity likely occurred during periods of abrupt climate change throughout the last Ice Age.
Hula hooping is so commonplace that we may overlook some interesting questions it raises: 'What keeps a hula hoop up against gravity?' and 'Are some body types better for hula hooping than others?' A team of mathematicians explored and answered these questions with findings that also point to new ways to better harness energy and improve robotic positioners.
A special report outlines opportunities to enhance justice in genomics, toward a world in which genomic medicine promotes health equity, protects privacy, and respects the rights and values of individuals and communities.
Scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.
Obesity is a chronic, complex disease defined by excessive fat deposits that can impair the health of an individual. Obesity increases the risk of diabetes, hypertension, heart disease, bone health, and even reproduction. It also increases the risk of certain cancers and greatly influences quality of living, such as sleeping and moving.
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A multi-institutional team of scientists has developed a free, publicly accessible resource to aid in classification of patient tumor samples based on distinct molecular features identified by The Cancer Genome Atlas (TCGA) Network.
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