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Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier. The findings demonstrate the potential of this technology to pave the way for future treatments for a wide range of conditions such as Alzheimer's disease, amyotrophic lateral sclerosis, brain cancer, and drug addiction.
A telehealth company partnered with a pharmacy that lacked a required license, raising doubts about the safety and efficacy of the weight-loss medicines it mailed to patients.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.
Broken Heart Syndrome mimics symptoms of a heart attack. It can strike after a stressful event, such as the loss of a loved one, a physical shock, or prolonged anxiety. The good news: It's treatable.
Scientists in Spain detected Enterovirus C105 (EV-C105), a rare virus linked to respiratory and possible neurological illness in children, highlighting the emergence of a genetically distinct viral strain.
Stress-induced cardiomyopathy mimics symptoms of a heart attack, even elevating a key 'heart attack' enzyme in blood. It's born of a stressful event, such as loss of a loved one or a dramatic experience or shock. It's most common in women over 50. The good news: People usually make a full recovery.
Bringing aromas indoors with the help of chemical products -- yes, air fresheners, wax melts, floor cleaners, deodorants and others -- rapidly fills the air with nanoscale particles that are small enough to get deep into your lungs, engineers have found over a series of studies.
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Bringing aromas indoors with the help of chemical products -- yes, air fresheners, wax melts, floor cleaners, deodorants and others -- rapidly fills the air with nanoscale particles that are small enough to get deep into your lungs, engineers have found over a series of studies.
AI-assisted mental health care is evolving, with ChatGPT-4 outperforming therapists in empathy and cultural competence, raising implications for psychotherapy.
Much will depend, in the Indian context, on the vision, core values and guiding principles of how the One Health Mission approaches multi-sectoralism and transdisciplinarity.
Researchers found that probiotics may enhance endurance, recovery, and immune function in athletes, but the evidence for strength and power performance remains limited.
Animals are not just inhabitants of the natural world -- they are its architects. A new study has revealed how hundreds of species shape the landscapes we depend on, from vast termite mounds visible from space to hippos carving drainage systems and beavers creating entire wetlands.
A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children with neuroblastoma, with one patient remaining cancer-free for over 18 years.
the results of our reader poll on OSHA - should it stay or should it go now? (apologies to the Clash ) As we reported a few days ago, Representative Andy Biggs R AZ introduced HR 86 on, February 2nd; the bill would abolish the Occupational Safety and Health Administration (OSHA) , a Department of Labor agency tasked with overseeing workplace safety.
A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.
A rare discovery of a nearly complete skull in the Egyptian desert has led scientists to the 'dream' revelation of a new 30-million-year-old species of the ancient apex predatory carnivore, Hyaenodonta.
Researchers used machine learning models to predict preterm birth risk, identifying linear SVMs as the most accurate, with key predictors including inflammation and blood composition markers.
Important Information about Final Grading of Spring 2025 (POT S4) Classes | Faculty/Staff News Now | Online final grading for Spring 2025 - POT S4 (First 6 weeks) begins on Thursday, Feb. 20 via FlashFAST. Grading is also now available for any Spring 2025 course section that was flexibly scheduled. The deadline for grading submission is 11:59 p.m. on Tuesday, Feb. 25.
Therapy dog programs show promise in supporting university students' mental health, reducing anxiety and depression during their first semester adjustments.
At the Kanchi Kamakoti CHILDS Trust Hospital in Chennai, doctors say that structured movement-based interventions support faster physical and psychological recovery of critically ill children
The raids were undertaken on February 13, 2025 in Jammu and Kashmir, Delhi, Himachal Pradesh and Haryana in the case related to Raees Ahmed Bhat and others
Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) in their current publication in Nature.
Nature Reviews Earth & Environment, Published online: 18 February 2025; doi:10.1038/s43017-024-00633-y Marine fisheries and aquaculture support global food security. This Review considers how fishery and aquaculture activities influence marine nutrient dynamics and trophic structure, with implications for biogeochemical cycles from local to global scales.
A new study reveals that diabetes significantly accelerates the emergence and spread of antibiotic-resistant Staphylococcus aureus infections, highlighting a major public health concern.
Have you ever laid down in bed only to be kept awake by the constant thudding pulse in your head? Usually, its not a cause for alarm, but if it occurs all the time, it could be pulsatile tinnitus, which affects an estimated 3 million to 5 million Americans. 1 This condition is characterized by hearing a rhythmic sound in your ears that echoes each heartbeat.
Many are now well aware of the health consequences of overconsuming unsaturated fats in our diet. However, what many don't realize is that the fat composition within the human body has fundamentally changed over the past century. There has been a drastic shift in the sources of our dietary fat intake from a diet historically rich in saturated fats to one now dominated by polyunsaturated fats.
A nut used in herbal tea has become a hydrogel perfect for a variety of biomedical uses in new research from the University of Chicago Pritzker School of Engineering (UChicago PME) and UChicago Chemistry Department.
Ansar Ahmed, State Project Director, Integrated Disease Surveillance Programme, told The Hindu that there was no need to panic, as only those who were in contact with the infected birds and health workers examining poultry workers are at risk
Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.
Congenital Diaphragmatic Hernia is a rare condition where a defect in the diaphragm allows abdominal organs to move into the chest cavity, impairing lung and heart development
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